Silk microneedles could vaccinate farmed fish with less stress
Researchers at MIT and the US Department of Agriculture have made water-resistant microneedles from food-grade silk. The peer-reviewed paper in ACS Nano shows the needles can deliver cargos such as bacterial vaccines.
Professor Benedetto Marelli of MIT's Department of Civil and Environmental Engineering led the work. The needles lightly penetrate fish skin, stay attached and then decompose. Today's most effective method uses metal needles, and workers must sedate and inject fish one by one. The team calls its approach "potentially better", but the evidence comes from lab work, and it has not been tested on farms.